Day 10: 26 Days of March of Dimes

Prematurity Research

• Researchers are working to identify the causes of premature birth.
• In progress: new treatments to prevent or halt preterm labor.
• Medical breakthroughs improve the care of premature babies.

Preventing premature birth

Premature birth is a complex problem with no single solution. More than half a million babies are born prematurely each year in the United States. In up to 40 percent of cases, the cause is unknown. March of Dimes researchers are seeking the causes of prematurity as a step toward developing ways to prevent it.

Prematurity research initiative 

In 2005, the March of Dimes began the Prematurity Research Initiative (PRI), which funds research into the causes of prematurity. More than $15 million has been awarded to 43 grantees over the past 6 years. Some PRI grantees are exploring how genetics or a combination of genetic and environmental factors may influence a woman’s chances of going into labor prematurely. Others are examining how infections may trigger early labor. One of every three premature births can be attributed an infection in a woman’s uterus, which may have presented with no symptoms.

Treating preterm labor

PRI grantees also are exploring new ways to treat preterm labor. Some are studying how the body normally suppresses uterine contractions until a baby reaches full term, so that new drugs can be developed to prevent or stop preterm labor.

Saving preemies’ lives

In addition to PRI support, the March of Dimes funds prematurity research through its national research program. Grantees are improving the care of premature babies by developing new ways to help prevent or treat common complications of prematurity. For example, researchers helped develop surfactant treatment, which has saved tens of thousands of premature babies with breathing problems.

Transdisciplinary research centers
A novel approach to address the complex problem of preterm birth and the resulting prematurity is a transdisciplinary effort within which many diverse disciplines work together by integrating research. By working together, they can examine this problem from new perspectives in ways that individual studies do not allow. The March of Dimes has established the first transdisciplinary research center and plans to promote the establishment of several more.

source:  http://www.marchofdimes.com/research/prematurity-research.aspx

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